The sailing leg is 145 nautical miles from Lady Barron on Flinders Island to the resort village of Coles Bay, from where the runners have a 33km bushland run to the peak of Mt Freycinet and back.
First away Lady Barron on Flinders Island, after winning the 90 nautical mile leg from Beauty Point on Friday, was the little catamaran Slingshot, skippered by Steve Walker, from Wynyard.
After arriving at Lady Barron at 2am, Slingshot headed to sea again in a 10-15 knot south-easterly breeze at 08.25am.
Orana Respite Mersey Pharmacy, the 14m catamaran owned by designer Rob Chamberlin from Queensland and Terry Travers from Devonport, left at 08:54am in second place after a fast run to Mt Strzelecki and back by runners Nigel Aylott and Michael Wheatley.
The big Jervis Bay catamaran Incinerator, skippered by Kanga Birtles, was third to leave at 10:34am, the two women runners, Jacqui Guy from Hobart and Louise Proven from Scotland, being overtaken on the tough maintain run at night.
Last boat to leave Lady Barron was Genrx, a 10.25m Van de Stadt sloop in the Cruising Division, with a Launceston team aboard.